Ovulation disorders affect the release of eggs from the ovaries, leading to irregular, infrequent, or absent menstrual cycles. Previously named polycystic ovary syndrome (PCOS), polyendocrine metabolic ovarian syndrome (PMOS) is one of the most common causes.
PMOS/PCOS and other ovulation disorders present differently from patient to patient. For some women the primary concern is irregular periods, for others, it is difficulty conceiving, and for many it is a combination of symptoms that have gone unaddressed for too long. Dr Rozen takes a thorough approach to diagnosis and develops a management plan that addresses each patient’s individual circumstances.
PMOS/PCOS is a hormonal condition characterised by an imbalance in reproductive hormones, often combined with insulin resistance and a genetic predisposition. It is one of the most common causes of irregular periods and fertility challenges in women of reproductive age. Despite the name, not all women with PMOS/PCOS have cysts on their ovaries, and the condition presents differently in different people.
Please note polyendocrine metabolic ovarian syndrome (PMOS) has replaced the name polycystic ovary syndrome (PCOS), following a global consensus process led by researchers at Monash University. The purpose of the new name is to better reflect the metabolic and endocrine dimensions of the condition. There is a three-year transition period underway, during which both names can be used and refer to the same condition. PMOS will be fully implemented in 2028.
Diet and exercise to manage weight and reduce insulin resistance are often an important first step, particularly in PMOS/PCOS. Even modest improvements in weight and metabolic health can have a meaningful impact on hormone balance and ovulation.
Medications such as Clomiphene and Letrozole can be used to stimulate ovulation in women who are not ovulating regularly.
Metformin is commonly used in PMOS/PCOS to improve insulin resistance, which can help regulate menstrual cycles and support ovulation.
The contraceptive pill can be used to regulate menstrual cycles and reduce androgen levels in women who are not currently trying to conceive.
For women facing infertility as a result of ovulation disorders, assisted reproductive technologies including IVF may be recommended where other treatments have not been successful.
In cases of PMOS/PCOS that have not responded to other treatments, a surgical procedure called ovarian drilling may be considered. This is typically only explored when other options have been exhausted.
PMOS/PCOS presents differently from patient to patient, and it is often diagnosed too quickly or missed altogether. Dr Rozen takes a thorough approach to diagnosis, combining blood tests, pelvic ultrasound, and a full picture of each patient’s symptoms and history before recommending a management plan.
Whether the priority is regulating cycles, managing symptoms like acne or hair changes, or improving the chance of conceiving, Dr Rozen tailors treatment accordingly. This may mean lifestyle and metabolic support, medication, or assisted reproductive technology, depending on what each patient is trying to achieve.
PMOS/PCOS is a chronic condition with implications that extend beyond fertility, including metabolic and long-term health risks. Dr Rozen approaches management as an ongoing relationship, adjusting the plan as a patient’s goals, life stage, and health needs change over time.
“PMOS is one of those conditions that can feel overwhelming because it touches so many different aspects of health. I want every patient to leave their appointment with a clear understanding of what’s happening and a plan that feels manageable and right for them.”
– Dr Genia Rozen, Fertility Specialist, Genea Melbourne City and Frankston
