December 4, 2025

Severe Ovarian Hyperstimulation Syndrome (OHSS) After Gonadotrophin Releasing Hormone Agonist (GnRHa) Triggering

Ovarian Hyperstimulation Syndrome is something we work hard to prevent, particularly in women who are at high risk of responding strongly to stimulation. Although a GnRH agonist trigger with a freeze-all approach is our most effective prevention strategy, this study shows that severe OHSS can still occur in a small number of patients.

Understanding who remains vulnerable, even when best-practice protocols are used is essential to improving safety in IVF.

Read the abstract